4 sources·Science

Colossal's Groundbreaking De-Extinction: Dire Wolf Pups Introduced

Colossal has successfully birthed three genetically engineered dire wolf pups, reviving an extinct species and prompting discussions on the potential ecological implications.

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  1. De-extinction company announces that the dire wolf is back

    While this is being portrayed as the return of the dire wolf, these animals are primarily a variant of grey wolves, as many of the genetic changes that create their large size and pale coat already exist in some grey wolf populations.

    De-extinction company announces that the dire wolf is back

    ARS TechnicaARS Technica·11d
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    This source consistently reports facts with minimal bias, demonstrating high-quality journalism and accuracy.
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  2. Dire wolf returns from extinction? Company reveals 'magic' it's using to bring back species

    Colossal shows "that our end-to-end (de-extinction) toolkit that we talked about with the mouse works, but now it's working with ancient DNA and it's been pretty incredible."

    Dire wolf returns from extinction? Company reveals 'magic' it's using to bring back species

    USA TODAYUSA TODAY·12d
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    This source consistently reports facts with minimal bias, demonstrating high-quality journalism and accuracy.
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  1. The New Yorker
  2. ARS Technica
  3. Daily Caller
  4. USA TODAY

Updated: Apr 7th, 2025, 5:42 PM ET

Summary

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Dallas-based biotech company Colossal has unveiled three genetically engineered dire wolf pups, marking the first success in its de-extinction initiative. By editing genes from grey wolves, the pups showcase traits reminiscent of their extinct ancestors, including size and coat color. While hailed as a significant breakthrough, experts note the new dire wolves possess many traits of grey wolves and may lack instinctual behaviors of their ancient relatives. As Colossal explores de-extinction technologies, ethical questions arise regarding the potential ecological roles these recreated species could occupy. The dire wolf, which went extinct around 13,000 years ago, remains a symbol of conservation efforts.


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  • Colossal Biosciences has announced the successful 'de-extinction' of the dire wolf, leveraging advanced genetic technologies to edit the genomes of existing grey wolves, rather than recreating the species from scratch. This represents a significant milestone in the field of genetic engineering.

  • The new dire wolves, born from closely edited grey wolf genes, reflect a blend of ancient traits and modern characteristics, symbolizing a commitment to conservation and showcasing advancements in biotechnological methods.

  • The project not only highlights successful advancements in genetic engineering but also aims to raise awareness of the conservation of wolves, emphasizing their critical role in current ecosystems and the importance of biodiversity.


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Colossal's Groundbreaking De-Extinction: Dire Wolf Pups Introduced - Pano News