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49ers Lose McCaffrey and Mason to Injuries, Struggling in NFC West
San Francisco 49ers star running back Christian McCaffrey has been placed on injured reserve due to a PCL injury, alongside backup Jordan Mason suffering an injury.
49ers are nearing rock bottom following a blowout loss and the injury to McCaffrey
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Christian McCaffrey’s backup lands on IR as 49ers lose 2 running backs in roller-coaster season
49ers running back Christian McCaffrey headed to IR with an injured right knee

Christian McCaffrey injury update: 49ers RB placed on injured reserve with PCL injury
Overview
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The San Francisco 49ers announced that running back Christian McCaffrey will miss the rest of the regular season due to a PCL injury, joining backup Jordan Mason on injured reserve. This adds to the team's injury woes as they sit in last place in the NFC West with a 5-7 record. McCaffrey's absence, following previous Achilles tendon issues earlier in the season, leaves rookie Isaac Guerendo as the lead back. The 49ers will need to rally for a playoff push amid these setbacks and have faced difficulties maintaining their running game.
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